187 research outputs found

    Імунологічні аспекти діагностики та лікування постгістеректомічного синдрому

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    В статье представлены данные клинико-иммунологического, вегетологического, психологического статуса 80 женщин, страдающих постгистерэктомическими расстройствами с целью поиска оптимальных подходов к терапии. Установлено, что постгистерэктомический синдром сопровождается различными изменениями нейровегетативной регуляции, коррелирующими с гормонально-иммунологическими нарушениями. Стабильные положительные клинико-иммунологические сдвиги у пациенток с постгистерэктомическим синдромом показали высокую эффективность включения иммунокорригирующих препаратов для оптимизации терапевтических мероприятий в борьбе с указанной патологией.Basing on clinical, immunological, vegetologycal investigations in 80 women with posthysterectomy disorders with the purpose of search of optimum pathogenetic approaches to therapy. It has been found that a posthysterectomy syndrome is accompanied by the different changes neyrovegetatic regulationand also psychoemotional disorders. New important hormonal and immunological aspects of pathogenesis were determinated. Stable positive clinical and immunological changes at patients with a postgysterektomy syndrome showed high effect of including of immunological correction for the complex of treatment of patients with this pathology

    Thermal energy transfer around buried pipe infrastructure

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    Decarbonisation of heating is essential to meet national and international greenhouse gas emissions targets. This will require adoption of a range of solutions including ground source heat pump and district heating technologies. A novel route to these solutions includes dual use of buried infrastructure for heat transfer and storage in addition to its primary function. Water supply and wastewater collection pipes may be well suited for thermal energy applications being present in all urban areas in networks already in proximity to heat users. However, greater understanding of their potential interactions with surrounding heat sources and sinks is required before full assessment of the energy potential of such buried pipe networks can be obtained. This paper presents an investigation into the thermal interactions associated with shallow, buried water filled pipes. Using the results of large scale experiments and numerical simulation it is shown that soil surface ambient conditions and adjacent pipes can both act as sources or sinks of heat. While conduction is the main mechanism of heat transfer in the soil directly surrounding any pipe, any adjacent water filled pipes may lead to convection becoming important locally. In the test case, the thermal sphere of influence of the water filled pipe was also shown to be large, at in excess of 4 m over a timescale of 4 months. Taken together, these points suggest that design and analysis approaches when using water supply and wastewater collection networks for heat exchange and storage need careful consideration of environmental interactions, heat losses and gains to adjacent pipes or other infrastructure, and in ground conditions for a number of pipe diameters from any buried pipe

    Upper- and mid-mantle interaction between the Samoan plume and the Tonga-Kermadec slabs

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    Mantle plumes are thought to play a key role in transferring heat from the core\u2013mantle boundary to the lithosphere, where it can significantly influence plate tectonics. On impinging on the lithosphere at spreading ridges or in intra-plate settings, mantle plumes may generate hotspots, large igneous provinces and hence considerable dynamic topography. However, the active role of mantle plumes on subducting slabs remains poorly understood. Here we show that the stagnation at 660 km and fastest trench retreat of the Tonga slab in Southwestern Pacific are consistent with an interaction with the Samoan plume and the Hikurangi plateau. Our findings are based on comparisons between 3D anisotropic tomography images and 3D petrological-thermo-mechanical models, which self-consistently explain several unique features of the Fiji\u2013Tonga region. We identify four possible slip systems of bridgmanite in the lower mantle that reconcile the observed seismic anisotropy beneath the Tonga slab (VSH4VSV) with thermo-mechanical calculations

    The Potential for Heat Recovery and Thermal Energy Storage in the UK Using Buried Infrastructure

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    Dispersed space heating alone accounts for 40% of UK energy use and 20% of CO2 emissions. Tackling heating and building cooling demands is therefore critical to achieve net zero ambitions in the UK. The most energy efficient way to decarbonise heating and cooling is through the use of ground source heat pumps and district heating technology. However, capital costs are often high, sometimes prohibitively so. To reduce investment costs, it is proposed to use buried infrastructure as sources and stores of thermal energy. Barriers to this innovative approach include lack of knowledge about the actual net amount of recoverable energy, and impacts on the primary function of any buried infrastructure, as well as the need for new investment and governance strategies integrated across the energy and infrastructure sectors. Additional opportunities from thermal utilisation in buried infrastructure include the potential mitigation of damaging biological and/or chemical processes that may occur. This paper presents a first assessment of the scale of the opportunity for thermal energy recovery and storage linked to new and existing buried infrastructure, along with strategic measures to help reduce barriers and start the UK on the journey to achieving of its infrastructure energy potential

    Prediction of organic combined sewer sediment release and transport

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    Accurate predictions of sediment loads released by sewer overflow discharges are important for being able to provide protection to vulnerable receiving waters. These predictions are sensitive to the estimated sediment characteristics and on the site-conditions of in-pipe deposit formation. Their application without a detailed analysis and understanding of the “initial conditions” under which in- sewer deposits were formed normally results in very poor estimations. In this study, in-sewer sediment samples deposited during dry-periods in a combined sewer system were collected, and their properties assessed. Parameters in the sediment transport relationship first proposed by Skipworth for in-pipe deposits were estimated based on simulating the in-pipe deposit formation conditions in laboratory erosion tests. The measured parameters were then used to simulate sediment transport through a small combined sewer network for a number of rain events for which rainfall, hydraulic and water quality data were available. Results showed that the model of Skipworth can provide good predictions of the sediment loads released from such in-sewer deposits. The experimentally-derived calibration parameters used with Skipworth’s model allowed for a realistic simulation of the in-sewer sediment behaviour and so can be used to accurately estimate the sediment load released from combined sewer systems during rainfall events

    LSST: from Science Drivers to Reference Design and Anticipated Data Products

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    (Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg2^2 field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5σ\sigma point-source depth in a single visit in rr will be 24.5\sim 24.5 (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg2^2 with δ<+34.5\delta<+34.5^\circ, and will be imaged multiple times in six bands, ugrizyugrizy, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg2^2 region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to r27.5r\sim27.5. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie
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